IBD: Isolation By Distance
v 1.52 (March 18, 2004)
Andrew J. Bohonak
San Diego State University
Please note that this program has been superceded by IBDWS, which has many additional features.
 | Bohonak, A. J. 2002. IBD (Isolation By Distance): A program for analyses of isolation by distance. Journal of Heredity 93: 153-154.
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IBD is a fast and simple application for analyzing
(genetic) isolation by (geographic) distance.
- For diploid/codominant marker data sets (e.g., allozymes, microsatellites), IBD will calculate genetic distance statistics between all pairs of populations (FST, Slatkin's M, Rousset's distance).
- For any data set, if geographic distances between all population pairs are entered, IBD will provide analyses of "isolation by distance" as follows:
- The significance between the distance similarity matrix and the geographic distance matrix is assessed with a Mantel Test. This answers the question: Is genetic similarity between population pairs associated with the distance between them?
- The strength of the relationship is determined by regressing all pairwise genetic similarity values against their corresponding geographic distances, using reduced major axis regression. Confidence intervals are calculated using a number of different approaches, including resampling algorithms.
- A third matrix can also be entered to assess the effects of another variable (e.g., population fragmentation, subspecies affiliation, alternative measures of geographic connectivity) on genetic distance. IBD will calculate partial correlation coefficients for {genetic distance} on this variable and geographic distance.
This program has been replace by IBDWS (IBD Web Service) at http://ibdws.sdsu.edu/
IBDWS is a web-based version of IBD with bug fixes, downloadable Postscript scatterplots, the ability to process raw DNA data, and an easy to use interface. PC-based versions of IBD still work very well on the operating systems they were compiled for, but they will no longer be updated with new features.
Final PC-based version of IBD: 1.52 of 18 March 2004
IBD Manual (pdf format)
IBD for PPC Macintosh (binhexed, self expanding achive)
IBD for Windows (self expanding achive)
Larger data sets?
The IBD downloads below have a maximum of 500 populations instead of
100 populations (in the standard PC version). (Memory requirements will be higher.)
MAX 500 POPULATIONS IBD for PPC Macintosh (binhexed, self expanding achive)
MAX 500 POPULATIONS IBD for Windows (self expanding achive)
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