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THOMAS SCOTT



Vice President for Research, Graduate and Research Affairs
and Professor
Ph.D., Duke University
Department of Psychology
Cell & Molecular Doctoral Program

(619) 594-5142

Email - trscott@sciences.sdsu.edu




Neural Coding of Taste Activity and the Neural Bases of Eating and Reward

We are using single neuron recording techniques to investigate the nature of the neural code by which taste stimuli are identified in rodents and primates. The taste code changes according to the experiences and physiological needs of the animal. We monitor those changes in cortical areas that are responsible for the pleasure of eating as we manipulate gastric, duodenal and circulatory factors associated with satiety. Thus we can determine how taste sensations and the rewards of eating are influenced by digestive processes.

Recent publications

Books:

Fisher, C. and Scott, T. R. (1997) Food Flavours: Biology and Chemistry. Cambridge,
England: The Royal Society of Chemistry.

Scott, T.R. and DiLorenzo, P.M. (guest editors) (2000) Special issue of Physiology and
Behavior. Elsevier Press.

Journal Articles & Chapters:

McCaughey, S.A. and Scott, T.R. (1998) The taste of salt. Neuroscience and
Biobehavioral Reviews, 22: 663-676.

Flynn, M.C., Scott, T.R., Pritchard, T.C., and Plata-Salamán, C.R. (1998) Mode of action
of OB protein (leptin) on feeding. American Journal of Physiology, 275: R174-179.

Karadi, Z., Scott, T.R., Oomura, Y., Nishino, H., Lenard, L., and Aou, S. (1998)
Neurochemistry of amygdaloid cells responsive to taste and smell. In C. Murphy (Ed.),
Olfaction and Taste, Vol. XII. New York: New York Academy of Sciences Press, pp.
488-492.

Scott, T.R., Giza, B.K., and Yan. J. (1998) Responses to bitter stimuli in the macaque
cortex. In C. Murphy (Ed.), Olfaction and Taste, Vol. XII. New York: New York Academy
of Sciences Press, pp. 498-501.

Scott, T.R., Giza, B.K., and Yan, J. (1999) Gustatory neural coding in the cortex of the
alert cynomolgus macaque: The quality of bitterness. Journal of Neurophysiology, 81:
60-71.

Scott, T.R. and Plata-Salamán, C.R. (1999) Taste in the monkey cortex. Physiology and
Behavior, 67: 489-511.

McCaughey, S.A. and Scott, T.R. (2000) Rapid induction of sodium appetite modifies
taste-evoked activity in the rat nucleus of the solitary tract. American Journal of
Physiology, 279: R1121-1131.

Scott, T.R. and Giza, B.K. (2000) Issues of neural coding in taste: Where they stand.
Physiology and Behavior, 69: 65-76.

Scott, T.R. and DiLorenzo, P.M. (2000) Act III: The role of Robert P. Erickson in taste
research. Physiology and Behavior, 69: 1-2.

Scott, T.R. and Verhagen, J.V. (2000) Taste as a factor in the management of nutrition.
Nutrition, 16: 874-885.

Scott, T.R. and Plata-Salamán, C.R. (2000) Recording from single neurons in primary
taste cortex of the alert macaque. In S.A. Simon and M. Nicolelis (Eds.), Methods in
Chemosensory Research. Boca Raton, FL: CRC Press, in press.

Scott, T.R. (2000) The physiology of taste in the macaque. In P. Given and D. Paredes
(Eds.), Chemistry of Taste: From Molecules to Perception to Preference. Washington,
DC: American Chemical Society, in press.

Scott, T.R. (2000) Taste: Behavioral and functional aspects. In A.E. Kazdin (Ed.),
Encyclopedia of Psychology, New York: Oxford University Press, in press.

Smith, D.V. and Scott, T.R. (2000) Gustatory neural coding. In R.L. Doty (Ed.),
Handbook of Olfaction and Gustation, 2nd Edition. New York: Marcel Dekker, in press.

Rolls, E.T. and Scott, T.R. (2000) Central taste anatomy and neurophysiology. In R.L.
Doty (Ed.), Handbook of Olfaction and Gustation, 2nd Edition. New York: Marcel
Dekker, in press.

Scott, T.R. (2000) The neural basis of taste. In N.J. Smelser and P.B. Baltes (Eds.),
International Encyclopedia of Social and Behavioral Sciences. Oxford, UK: Elsevier
Science, in press.

Note: Entrez Medline entries for a particular Author name may correspond with multiple authors with the same initials. Also, the list is limited to entries stored in the Entrez Medline Database and may not accurately reflect the true number of publications