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Neural Coding of Taste Activity and the Neural Bases of Eating and
Reward
We are using single neuron recording techniques to investigate the nature of the
neural code by which taste stimuli are identified in rodents and primates. The taste
code changes according to the experiences and physiological needs of the animal.
We monitor those changes in cortical areas that are responsible for the pleasure
of eating as we manipulate gastric, duodenal and circulatory factors associated with
satiety. Thus we can determine how taste sensations and the rewards of eating are
influenced by digestive processes.
Recent publications
Books:
Fisher, C. and Scott, T. R. (1997) Food Flavours: Biology and Chemistry. Cambridge,
England: The Royal Society of Chemistry.
Scott, T.R. and DiLorenzo, P.M. (guest editors) (2000) Special issue of Physiology
and
Behavior. Elsevier Press.
Journal Articles & Chapters:
McCaughey, S.A. and Scott, T.R. (1998) The taste of salt. Neuroscience and
Biobehavioral Reviews, 22: 663-676.
Flynn, M.C., Scott, T.R., Pritchard, T.C., and Plata-Salamán, C.R. (1998) Mode
of action
of OB protein (leptin) on feeding. American Journal of Physiology, 275: R174-179.
Karadi, Z., Scott, T.R., Oomura, Y., Nishino, H., Lenard, L., and Aou, S. (1998)
Neurochemistry of amygdaloid cells responsive to taste and smell. In C. Murphy (Ed.),
Olfaction and Taste, Vol. XII. New York: New York Academy of Sciences Press, pp.
488-492.
Scott, T.R., Giza, B.K., and Yan. J. (1998) Responses to bitter stimuli in the macaque
cortex. In C. Murphy (Ed.), Olfaction and Taste, Vol. XII. New York: New York Academy
of Sciences Press, pp. 498-501.
Scott, T.R., Giza, B.K., and Yan, J. (1999) Gustatory neural coding in the cortex
of the
alert cynomolgus macaque: The quality of bitterness. Journal of Neurophysiology,
81:
60-71.
Scott, T.R. and Plata-Salamán, C.R. (1999) Taste in the monkey cortex. Physiology
and
Behavior, 67: 489-511.
McCaughey, S.A. and Scott, T.R. (2000) Rapid induction of sodium appetite modifies
taste-evoked activity in the rat nucleus of the solitary tract. American Journal
of
Physiology, 279: R1121-1131.
Scott, T.R. and Giza, B.K. (2000) Issues of neural coding in taste: Where they stand.
Physiology and Behavior, 69: 65-76.
Scott, T.R. and DiLorenzo, P.M. (2000) Act III: The role of Robert P. Erickson in
taste
research. Physiology and Behavior, 69: 1-2.
Scott, T.R. and Verhagen, J.V. (2000) Taste as a factor in the management of nutrition.
Nutrition, 16: 874-885.
Scott, T.R. and Plata-Salamán, C.R. (2000) Recording from single neurons in
primary
taste cortex of the alert macaque. In S.A. Simon and M. Nicolelis (Eds.), Methods
in
Chemosensory Research. Boca Raton, FL: CRC Press, in press.
Scott, T.R. (2000) The physiology of taste in the macaque. In P. Given and D. Paredes
(Eds.), Chemistry of Taste: From Molecules to Perception to Preference. Washington,
DC: American Chemical Society, in press.
Scott, T.R. (2000) Taste: Behavioral and functional aspects. In A.E. Kazdin (Ed.),
Encyclopedia of Psychology, New York: Oxford University Press, in press.
Smith, D.V. and Scott, T.R. (2000) Gustatory neural coding. In R.L. Doty (Ed.),
Handbook of Olfaction and Gustation, 2nd Edition. New York: Marcel Dekker, in press.
Rolls, E.T. and Scott, T.R. (2000) Central taste anatomy and neurophysiology. In
R.L.
Doty (Ed.), Handbook of Olfaction and Gustation, 2nd Edition. New York: Marcel
Dekker, in press.
Scott, T.R. (2000) The neural basis of taste. In N.J. Smelser and P.B. Baltes (Eds.),
International Encyclopedia of Social and Behavioral Sciences. Oxford, UK: Elsevier
Science, in press.
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